Anatomy lessons

Public anatomy lessons and the carnival: the anatomy theatre of Bologna.

Lessons learned from aligning two representations of anatomy

The objective of this study is to analyze the comparison, through their results, of two distinct methods applied to aligning two representations of anatomy. The same versions of FMA and GALEN were aligned by each method. 2199 concept matches were obtained by both methods. For matches identified by one method only (337 and 336 respectively), we analyzed the reasons that caused the other method t...

Functional anatomy of essential tremor: lessons from neuroimaging.

The neuropathogenetic processes underlying essential tremor appear to cause subtle morphologic changes in neural networks that include multiple brain structures, primarily the cerebellum, brain stem, frontal lobes, and thalamus. One of the main challenges of neuroimaging in essential tremor is differentiating disease-specific markers from the spectrum of structural changes that occur due to agi...

Enzyme activity and brain anatomy: lessons from HPRT deficiency.

Lesch-Nyhan disease is a rare, X-linked disorder, related to defi ciency of the purine salvage enzyme hypoxanthineguanine phosphoribosyltransferase (HPRT). In addition to uric acid overproduction, HPRT defi ciency aff ects motor and cognitive function and is associated with behavioural disturbances caused by unknown pathophysiological changes. Since it was fi rst described, it has been known th...

Development, learning and memory in large random networks of cortical neurons: lessons beyond anatomy.

1. Introduction 63 1.1 Outline 63 1.2 Universals versus realizations in the study of learning and memory 64 2. Large random cortical networks developing ex vivo 65 2.1 Preparation 65 2.2 Measuring electrical activity 67 3. Spontaneous development 69 3.1 Activity 69 3.2 Connectivity 70 4. Consequences of spontaneous activity : pharmacological manipulations 72 4.1 Structural consequences 72 4.2 F...